Job Description

At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

The Drug Metabolism and Pharmacokinetics (DMPK) department in the Nonclinical Research and Development (NCRD) department at BMS is seeking a highly skilled ADME scientist for a Senior/Principal Scientist position in Princeton, NJ.

Position Summary

As a Senior/Principal Scientist, you will be responsible for supporting discovery and development projects through leading the DMPK study design, strategy, and execution. You will collaborate closely with multiple departments across a diverse portfolio, including oncology, immunology, and neuroscience, to address drug development issues. With guidance, you will be responsible for preparing regulatory dossiers/responses and oversee drug metabolism and pharmacokinetics studies on multiple programs.

Depending on the candidate’s background and interest, this role may also involve the use of physiologically based pharmacokinetic (PBPK) modeling to support project needs and regulatory filing.

Roles and Responsibilities

Responsibilities will include, but are not limited to:

• Apply novel techniques and approaches to address DMPK issues

• Contribute to internal and outsourced DMPK activities by providing input on study design, data interpretation, and report review

• Depending on candidate’s experience, serve as an independent DMPK representative on cross-functional project teams and provide input on project strategies and development plans

• Collaborate closely with Clinical Pharmacology, Toxicology, Pharmacology, and other cross-functional groups to address project related issues

• Keep management apprised of project status and current scientific trends using written and oral summaries, as well as presentations.

Skills/Knowledge Required

• PhD degree in pharmacokinetics and/or drug metabolism or related field

• The Sr Scientist will need to have 2-5 years of experience in the field of DMPK, pharmacology, and/or modeling and simulation

• The Principal Scientist will need to have 5+ years of experience in the field of DMPK, pharmacology, and/or modeling and simulation

• Strong understanding of ADME, pharmacokinetics, and pharmacodynamics concepts

• Hands-on experience with in vitro and in vivo techniques used to characterize drug metabolism, transport, pharmacokinetics, and drug-drug interaction potential of drug candidates

• Ability to multi-task and work in a collaborative team environment

• Demonstrated hands-on experience with physiologically based pharmacokinetic (PBPK) modeling is a plus

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. 

Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture.

To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation.  Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment.  This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.

Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application or if you are applying to a role based in the U.S. or Puerto Rico and you believe that you are unable to receive a COVID-19 vaccine due to a medical condition or sincerely held religious belief, during or any part of the recruitment process, please direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

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